Thermally reversible xyloglucan gels as vehicles for nasal drug delivery

Discrete thermally responsive hydrogel-coated gold nanoparticles for use as drug-delivery vehicles

This report describes the development of optically responsive gold nanoparticles ( 60 nm in diameter) coated with a thermally responsive biocompatible hydrogel overlayer (20–90 nm thick). The hydrogel consists of a mixture of N-isoproprylacrylamide and acrylic acid; this copolymer can be tailored to exhibit a lower critical solution temperature (LCST) slightly above physiological temperature. W...

Thermally reversible colloidal gels for three-dimensional chondrocyte culture.

Healthy cells are required in large numbers to form a tissue-engineered construct and primary cells must therefore be increased in number in a process termed 'expansion'. There are significant problems with existing procedures, including cell injury and an associated loss of phenotype, but three-dimensional culture has been reported to offer a solution. Reversible gels, which allow for the reco...

Density Functional Theory Calculations of Functionalized Carbon Nanotubes with Metformin as Vehicles for Drug Delivery

Drug delivery by nanomaterials is an active emergent research area and CNTs draws considerable potential application owing to its unique quasi one-dimensional structure and electronic properties. Single walled carbon nanotubes and carbon fullerenes can be used in drug delivery due to their mechanical and chemical stability. The past few years, increasing attention by several reputed groups has ...

Polymeric micelles as drug delivery vehicles

Nerve guidance channels as drug delivery vehicles.

Nerve guidance channels (NGCs) have been shown to facilitate regeneration after transection injury to the peripheral nerve or spinal cord. Various therapeutic molecules, including neurotrophic factors, have improved regeneration and functional recovery after injury when combined with NGCs; however, their impact has not been maximized partly due to the lack of an appropriate drug delivery system...